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The pH of pharmaceutical suspensions significantly impacts product safety and efficacy. It influences bioavailability, chemical behavior, and microbial activity. Therefore, accurate pH control is crucial for maintaining quality and consistency. Measuring the pH of suspensions can be challenging due to the dispersed or particulate nature of samples and particle-induced sensor clogging, which affects measurement accuracy and sensor lifespan. To overcome these challenges and ensure reliable results, a specialist sensor is required.
The InLab® Max Pro-ISM by METTLER TOLEDO is designed specifically for such samples. Its clog-resistant junction maintains uniform electrolyte flow, and its chemically resistant HA glass membrane delivers accurate and stable pH measurements across extreme pH values. With an integrated temperature probe and ISM chip for data storage, this sensor further simplifies the measurement process and enhances data integrity. All these features and a few others ensure accurate and reliable pH measurements of pharmaceutical suspensions.
Our application note offers valuable insights for R&D researchers and QC personnel working with pharmaceutical suspensions. It highlights the challenges that come with conventional sensors and recommends the specialist sensor InLab Max Pro-ISM as the right choice for accurate and reliable pH measurements. The note also shares good electrochemistry practices for measurement and sensor maintenance, which can improve the efficiency and reliability of your processes.
Download it now to optimize your pH measurement process and ensure product quality.
Frequently Asked Questions
Why is measuring the pH of pharmaceutical suspensions important?
Measuring the pH of pharmaceutical suspensions is important because it can impact the safety and efficacy of the product. The pH value can affect the bioavailability, biological functions, microbial activity, and chemical behavior of the drug. Therefore, accurate pH control is necessary to ensure consistent quality and effectiveness of the medication.
What are the challenges of measuring the pH of pharmaceutical suspensions?
Measuring the pH of pharmaceutical suspensions can be challenging due to factors like particle interference, sensor clogging, and the risk of inaccurate readings. These issues can impact product quality and consistency if not addressed properly.
What are some good electrochemistry practices for measuring the pH of pharmaceutical suspensions?
Implementing good electrochemistry practices like regular calibration, use of fresh buffers, and proper sensor storage can be useful. These steps help mitigate measurement errors and maintain data reliability; download our application note now for more details.
